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The Istanbul Vision 2050 Action Plan was developed with a perspective that considers the challenges posed by multiple crises and follows a multi-scale planning framework

The chart simply becomes a faster way to access what the formula already tells you

Mixing mcg into a calculation that expects mg shifts the answer by 1000x a documented cause of users either taking a microscopic dose or a fatal-equivalent dose depending on which direction the unit error went

However, CF, PCD, and NCFB are rarer with incidences ranging from 1 in 20,000 for PCD, between 50 and 1,000 in 100,000 for NCFB, and around 160,000 individuals with CF worldwide (Nigro et al., 2024