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Thus, more GLP-1 leads to more insulin, which decreases blood-sugar levels

Zepbound should not be used with other tirzepatide-containing products or any GLP-1 receptor agonist medicines, and it has not been studied in patients with a history of pancreatitis, or with severe gastrointestinal disease, including severe gastroparesis

In data published in Obesity , researchers found adults receiving tirzepatide in three SURMOUNT trials did not experience worsening of depression throughout the studies

This eye disorder occurs when blood flow to the optic nerve is interrupted, leading to sudden vision loss in one eye, and is often referred to as a stroke of the optic nerve. According to research published by a team from Massachusetts Eye and Ear, a Harvard-affiliated hospital, patients who took Ozempic or Wegovy were found to be at a heightened risk for developing NAION