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10.1523/JNEUROSCI.2205-11.2011 169

vitamin B12 deficiency is not caused by a lack of vitamin B12 in your diet, youll usually need to have an injection of hydroxocobalamin every 2 to 3 months

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The Randle cycle essentially describes that when fatty acid oxidation is active there is a significant reduction in the uptake and utilization of glucose by inhibition of PDH flux, but it also works the other way around, so the production of acetyl-CoA from glycolysis will inhibit fatty acid oxidation through the generation of malonyl-CoA which can inhibit CPT I [99]