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Free Radic Res 2010;44:479-96

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To investigate the potential of tesamorelin as a treatment for NAFLD in people living with HIV, investigators at Massachusetts General Hospital and the US National Institutes of Health randomised 61 people living with HIV who had hepatic steatosis (liver fat content of 5% or greater) to receive either tesamorelin 2mg once daily or a placebo for 12 months, followed by open-label tesamorelin treatment for all participants for six months