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Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled, pilot trial

B12 deficiency can lead to weakness and fatiguetwo culprits that often keep people from sticking to their diet and exercise plans

PubMed: 18436195Clinical (RCT / meta-analysis) ref-8.Shahbazian H, Shayanpour S, Ghorbani A Evaluation of administration of oral N-acetylcysteine to reduce oxidative stress in chronic hemodialysis patients: A double-blind, randomized, controlled clinical trial

The likely direction is that undiagnosed disease raises B12, not that B12 causes the disease