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10.1016/j.redox.2022.102573 81 LauritsenK
5-Amino-1MQ Also known as: 5-amino-1-methylquinolinium, NNMTi TL;DR Increases intracellular NAD+ levels via NNMT inhibition (preclinical) Reduces body weight and white adipose mass in diet-induced obese mice Improves grip strength by up to 60% in aged mice when combined with exercise Suppresses lipogenesis in adipocytes without affecting food intake Community-Reported Side EffectsAnecdotal
Moreover, antioxidant potential of this phenolic compound increases mitochondrial biogenesis followed by reducing cell apoptosis, suggesting its beneficial role [134]
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