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Since no endothelial dysfunction nor gender differences were described for three different arms in literature, it would be important for future trials to address these items. This study shows a clear indication of the dangers that e-cigarettes containing nicotine pose to cardiovascular health, which are similar to if not exceeding the risks that are related to the use of regular cigarettes

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Tobacco production expansion and packaging material requirements are creating opportunities for cigarette packaging material integration across diverse tobacco categories requiring cost-effective packaging solutions and reliable material performance systems

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