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Before initiating any supplementation , discuss your plans with your healthcare provider, particularly if you have: Pre-existing medical conditions such as kidney disease, liver disease, or haemochromatosis (iron overload disorder) Multiple medications that may interact with high-dose vitamins or minerals A history of kidney stones , as calcium and vitamin D supplementation may increase recurrence risk Planned surgical procedures , as some supplements may need to be discontinued perioperatively Symptoms suggesting possible deficiency warrant medical evaluation rather than self-treatment

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