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Editorial overview: gastrointestinal: new frontiers in therapeutics for GI diseases and disorders-from microRNAs to novel pharmaceutics, to low FODMAP diets and microbiome

PMID: 36501363 | DOI: 10.3390/plants11233325 [14] Bounous G, Gold P

(2008, Neurology) tested SubQ native rhIGF-1 in adult ALS patients

"The growth hormone/IGF-1 axis is an attractive target for preserving muscle mass in cirrhosis, but the liver's dual role as both a GH effector organ and a metabolic clearance site means that any GH-axis intervention must account for the degree of hepatocellular dysfunction," according to the Endocrine Society's position statement on GH in chronic illness (Endocrine Society Clinical Practice Guideline, 2011)