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Vitamin D and vitamin A rely on the same receptors in each cell, so if the ingestion of vitamin A has been boosted during the acne treatment, then it is likely that you will need some vitamin D to help rebalance things out

A combination of oral zinc and a topical corticosteroid was also found to be more effective in repigmentation than the topical corticosteroid alone [100]

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While this has some inherent logic, it has not been fully explored whether it is valid to assume a linearity of the relationship between gene and serum UA in which genetic polymorphisms differentiating normal and high UA associated with, say, risk of gout are the same as those differentiating normal and low UA associated with risk of PD