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Several compounds with less theoretical concern about angiogenesis may serve as alternatives

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Such LBPs may also help transform microbiome-targeted therapies from adjuncts to scientifically validated, medical-grade modalities in preventing or slowing neurodegenerative and neuropsychiatric disease progression

Depending on cellular state and stress cues, TP53 can promote ferroptosis by repressing SLC7A11 to limit cystine uptake and GSH synthesis, inducing spermidine/spermine N1-acetyltransferase 1 ( SAT1 ) to enhance ROS generation through polyamine catabolism, and upregulating glutaminase 2 ( GLS2 ) to increase -ketoglutarate production and mitochondrial ROS 154-156