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Exp Gerontol 108:166173 Aydin AF, Kusku-Kiraz Z, Dogru-Abbasoglu S et al (2010a) Effect of carnosine against thioacetamide-induced liver cirrhosis in rat
Cysteine helps to neutralize chemicals known as aldehydes, which are produced by air pollutants, drugs, and also by the liver as a byproduct of alcohol metabolism
Safety Monitoring Recommendations Based on the available clinical trial data, clinicians prescribing orforglipron should: (1) counsel patients about expected GI side effects during dose escalation, (2) follow the recommended dose-titration schedule to minimize GI intolerance, (3) monitor for signs of pancreatitis and discontinue if suspected, (4) assess hepatic and renal function at baseline and periodically, (5) screen for personal or family history of MTC or MEN 2, and (6) review concomitant medications for potential CYP3A-mediated drug interactions
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