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They are prescription-only and should only be used under clinical supervision

Persistent swelling, redness lasting more than 48 hours, or signs of infection warrant immediate contact with your healthcare provider, as these may indicate lipohypertrophy or a localized reaction requiring site rest

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Treatment begins with 0.25 mg once weekly for four weeks, then increases to 0.5 mg for four weeks, followed by 1 mg for four weeks, then 1.7 mg for four weeks, before reaching the maintenance dose of 2.4 mg once weekly