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Finely chopping allium vegetables activates alliinase, rapidly generating allicin and downstream sulfides

Mechanism of Action: GLP-1 receptor agonists work through multiple physiological pathways: Central appetite suppression : These medications cross the blood-brain barrier and activate GLP-1 receptors in the hypothalamus and brainstem, reducing hunger signals and increasing satiety Gastric emptying delay : By slowing stomach emptying, patients experience prolonged fullness after meals Insulin secretion enhancement : Glucose-dependent insulin release improves glycemic control Glucagon suppression : Reduced glucagon secretion decreases hepatic glucose production Tirzepatide offers dual agonism at both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors, potentially providing enhanced weight loss efficacy compared to single-agonist medications

Int J Mol Sci 24(13):11038 Liu Z, Ren Z, Zhang J, Chuang C-C, Kandaswamy E, Zhou T, Zuo L (2018) Role of ROS and nutritional antioxidants in human diseases

Medicine (Baltimore) 12:40174024 Ethics declarations Conflict of interest On behalf of all authors, the corresponding author states that there is no conflict of interest