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WATCH | WHO recommends GLP-1 therapies for obesity: Health Canada has also listed known risks associated with the use of genuine GLP-1 products, including severe gastrointestinal problems, pancreatitis, worsening kidney injury and low blood sugar, particularly if combined with other medications

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43 Furthermore, echinacoside ameliorated D-GalN- and LPS-induced acute liver injury in mice by inhibiting apoptosis and inflammation, characterized by substantial inhibition of hepatocyte apoptosis and significant reduction in inflammatory markers, including myeloperoxidase, extracellular nucleosomes, high-mobility group box 1, and inflammatory cytokines in the plasma