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doi:10.1177/070674371205700703 Bhatia P, Singh N
Causes: oversupplementation Clinical features In infants: increased risk of necrotizing enterocolitis (NEC) High-dose supplementation: alteration of vitamin K metabolism anticoagulatory effects of warfarin risk of bleeding Increased incidence of heart failure, subarachnoid hemorrhage, and increased mortality [10] Therapeutic uses Nonalcoholic steatohepatitis: consider vitamin E for antioxidant effect Characteristics Synonyms Vitamin K 1 (phytomenadione, phytonadione, or phylloquinone) Vitamin K 2 (menaquinone) Substance class: naphthoquinones Chemical structure: Vitamin K1 Vitamin K2 Inactive precursors (provitamins): none Active form: vitamin K hydroquinone Sources Leafy green vegetables (vitamin K 1 ) Eggs, dairy, and meat (vitamin K 2 ) Synthesized in small amounts by intestinal bacteria Transport: via lipoproteins
Successful formulation of ghk copper peptide powder products requires attention to compatibility with other active ingredients, as certain combinations can either enhance or diminish efficacy
Several of the described splice variants (Pasternak, 2001) have no known cellular activity, although other variants have been described that affect the structure of the carboxyl-terminal cytoplasmic tail
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