Access this chapter Subscribe and save Buy Now Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others References Majumdar SK (2001) Bull Indian Inst His Med Hyderabad 31(1): 5770 Pendergrass M (2007) Nat Endocrinol Metabol 3(1):1 Cryer PE (2007) Nat Endocrinol Metabol 3(1):45 Onkamo P et al (2000) Diabetologia 43(10):13341336 Kishiyama CM, Chase H, Barker JM (2006) Rev Endocr Metab Disord 7(3):215224 The Diabetes Control and Complications Trial Research Group (1998) Ann Intern Med 128(7):517523 Cavaghan MK et al (2000) J Clin Investig 106:329333 Sadikot SM Jaslok Hospital and Research Centre, Mumbai United Kingdom Prospective Diabetes Study (1995) Diabetes 44:12491258 Banting FG et al (1922) Can Med Assoc J 12:141146 Banting FG, Best CHJ (1922) J Lab Clin Med 7:464472 Sanger F (1959) Science 129(3359):13401344 Lepore M et al (2000) Diabetes 49(12):21422148 De Len DD, Stanley CA (2007) Nat Clin Pract Endocrinol Metab 3:5768 The Diabetes Control and Complications Trial Research Group (1993) The

In addition to the beneficial effects on weight loss, prolonged water fasting has been shown to alter the gut microbiome [3], improve blood pressure [4, 5], and lower inflammation markers [6]
In beta cells, GLP-1 receptor activation raises cAMP in a glucose-dependent manner, a property that has made it a heavily studied model of GPCR signalling
Nevertheless, relevant RCT data from head-to-head comparisons are needed to test this hypothesis