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Inhaled metals such as nickel and chromium (commonly leached from heating coils) can deposit in lung tissue and have been associated with chronic airway inflammation, fibrosis, and elevated cancer risk ( 5 Mechanisms of lung damage in adolescent E-cigarette users Multiple mechanistic pathways underline the pulmonary damage observed in youth who vape, involving oxidative injury, inflammatory signaling, cellular toxicity, immune dysfunction, and interference with normal lung development ( ) and chemokines that drive inflammation in the respiratory tract ( E-cigarette exposure also inflicts DNA damage in lung cells and may impair the cells capacity for DNA repair

And President Andrew Jacksons signature made Indian removal the law of the land

Source: Guyuron B, Okado H, Alleyne B, et al

How else does weed affect the lungs