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For a deep (really deep) dive into the research studies that show the mechanics and efficacy of GLP-1 medications for weight loss, this video from Harvard Medical School gives in depth answers
At 340 Da, GHK-Cu can passively cross intact stratum corneum at low concentrations, but the order-of-magnitude greater dermal load achieved through micro-channel delivery is what the clinical literature on physically enhanced peptide delivery argues for
In work from Best et al, there was no evidence of attenuated global grey matter atrophy with 1 year of high-intensity progressive RT (2 sets of 6-8 repetitions at 70%85% of 1RM, either once or twice weekly) in 155 older women ( Increases in global brain volume in response to exercise is not well supported
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