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Literature search was conducted on PubMed, Scopus, Web of Science, and Embase using a combination of the keywords gut microbiota, gut microbiome, gut-brain axis, gut-kidney axis, gut-brain-kidney axis, chronic kidney disease, dysbiosis, therapy, metabolites, and neuroinflammation. Relevant studies were selected and synthesized in this narrative review

Inflammatory stimuli regulate caspase substrate profiles

Researchers should evaluate the product based on batch documentation, identity verification, and proper laboratory handling rather than powder color alone

Densitometric analysis of IBs is shown in Supplemental Figure 9B