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One new option, recently launched by aptly named startup Evolv, is Evolv GLP-1, which the company bills as a first of its kind oral GLP-1 dietary supplement

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A pre-specified analysis of SELECT trial, showed a clinically relevant reduction in albuminuria with a net treatment benefit of 10.7% (95% CI 13.2, 8.2) in patients with albuminuria at baseline suggesting a beneficial kidney effect of once-weekly subcutaneous semaglutide 2.4 mg in patients with overweight/obesity and established CVD, without diabetes [31]

The company has lined up a similar plan to commercialise its novel osteoarthritis knee pain candidate, MM-II in the US