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Langhans, 2000

Concentrated urine and reduced urinary frequency create conditions that may increase susceptibility to bacterial colonisation of the urinary tract

The present review has attempted to describe the risk factors of autism, the role of mitochondria in the progression of the disease, oxidative damage as a trigger point to initiate mitochondrial damage, genetic determinants of the disease, possible pathogenic pathways and therapeutic regimen in vogue and the developmental stage