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These results indicate excellent MRS data quality, with all measurements substantially exceeding the previously established criteria for the signal-to-noise ratio and linewidth ( Tau levels in the ACC were significantly lower in children with ASD than in TD controls (4.48 [0.95] for the ASD group and 5.08 [0.69] for the TD group, t = 3.36, p = 0.001) ( Figure 2 )

10.1016/j.neuron.2019.03.013 31

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