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Differs from phosphodiesterase5 (PDE5) inhibitors by acting centrally rather than primarily on peripheral vascular smooth muscle, making it a model for centrally mediated hypoactive sexual desire states
Inflammation in the CNS increases the risk of AD initiation and exacerbates the amyloid and tau pathology and the cognitive decline [12]
Resveratrol also regulates mitochondrial respiratory chain function, with mitochondrial complex I (CI) as a direct target of this molecule
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