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Studies examining safety and tolerability in rodents have generally not reported concerning toxicity signals at doses producing metabolic benefits, though comprehensive toxicology studies and long-term safety data are limited

Ferroptosis is fueled by iron-dependent phospholipid peroxidation and is regulated by various cellular metabolic pathways, including iron handling, redox homeostasis, mitochondrial activity, amino acid, lipid and sugar metabolism, and various disease-related signaling pathways (129)

Journal of Clinical and Aesthetic Dermatology, 2(3), 38