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IGF-1 in inducing hyperplasia or cellular mitosis upon injection to animal subjects

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7 The following further describes drug-specific recommendations from the ADA based on whether ASCVD or CKD/heart failure predominates clinically

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GLP-1R triggers various intracellular signaling pathways, such as the cAMP/PKA and PI3K/Akt pathways, by binding to endogenous GLP-1 or exogenous agonists, resulting in the enhancement of insulin secretion, inhibition of glucagon secretion, as well as anti-inflammatory and antioxidant stress response

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