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As of 2025, MOTS-c is still relatively under the radar compared to blockbuster drugs, but at LIVV we recognize its potential
Nrf2 staining and translocation For visualization and quantification of endogenous Nrf2 translocation into the nucleus, glass 96-well plates were coated with fibronectin (1 g/ml) (Sigma) and poly-l-ornithine (40 g/ml) over night
Similarly, in HaCaT model, apigenin was found to upregulate the expression of HBD-1, HBD-2, HBD-3, and LL-37, which may enhance antimicrobial peptide-mediated defenses under inflammatory conditions (Park C.-H
Diabetologia 58, 60414 (2014)
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